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Krüppel-Like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers

Podocyte injury is the inciting event in primary...

Premature T Cell Senescence in Pediatric CKD

An individual’s immune function, susceptibility to...

T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN

Th1 cells are central pathogenic mediators of crescentic...

G Protein-Coupled Receptor-G-Protein {beta}{gamma}-Subunit Signaling Mediates Renal Dysfunction and Fibrosis in Heart Failure

Development of CKD secondary to chronic heart failure (...

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron

Chloride transport by the renal tubule is critical for...

Rituximab for Severe Membranous Nephropathy: A 6-Month Trial with Extended Follow-Up

Randomized trials of rituximab in primary membranous...

mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells

Renal proximal tubular cells constantly recycle...

Loss of Cystic Fibrosis Transmembrane Regulator Impairs Intestinal Oxalate Secretion

Patients with cystic fibrosis have an increased...

Wnt7b Signaling from the Ureteric Bud Epithelium Regulates Medullary Capillary Development

The renal vasculature is integral to the physiologic...

Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function

The cardiac natriuretic peptides (NPs), atrial NP and B-...

Red Meat Intake and Risk of ESRD

Randomized controlled trials suggest that protein...

Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy

The amount of albumin filtered through the glomeruli and...

High Level of Fasting Plasma Proenkephalin-A Predicts Deterioration of Kidney Function and Incidence of CKD

High levels of proenkephalin-A (pro-ENK) have been...

Artículos Científicos RSS AJKD

Performance of the CKD-EPI Equation to Estimate GFR in a Longitudinal Study of Autosomal Dominant Polycystic Kidney Disease

GFR can only be measured indirectly.1 Because the gold...

Intraperitoneal Vancomycin Plus Either Oral Moxifloxacin or Intraperitoneal Ceftazidime for the Treatment of Peritoneal Dialysis−Related Peritonitis: A Randomized Controlled Pilot Study

Intraperitoneal administration of antibiotics is...

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