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Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection

Belatacept is a biologic that targets CD80/86 and...

Cold Shock Proteins Mediate GN with Mesangioproliferation

DNA binding protein A (DbpA) is a member of the human...

Pendrin--A New Target for Diuretic Therapy?

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Beyond EMT: Epithelial STAT3 as a Central Regulator of Fibrogenesis

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Preserving Residual Kidney Function in Hemodialysis Patients--Back in the Spotlight

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Predicting the Functionality and Form of a Dialysis Fistula

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Acidosis and Urinary Calcium Excretion: Insights from Genetic Disorders

Metabolic acidosis is associated with increased urinary...

Variable Cyst Development in Autosomal Dominant Polycystic Kidney Disease: The Biologic Context

Patients with autosomal dominant polycystic kidney...

Phospholipase A2 Receptor-Related Membranous Nephropathy and Mannan-Binding Lectin Deficiency

Most patients with idiopathic membranous nephropathy (...

Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx

Diabetic nephropathy (DN) is the leading cause of CKD in...

A FANCD2/FANCI-Associated Nuclease 1-Knockout Model Develops Karyomegalic Interstitial Nephritis

Karyomegalic interstitial nephritis (KIN) is a chronic...

Immune-Regulatory Molecule CD69 Controls Peritoneal Fibrosis

Patients with ESRD undergoing peritoneal dialysis...

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Donor and Recipient Views on Their Relationship in Living Kidney Donation: Thematic Synthesis of Qualitative Studies

Many donors and recipients report an improved...

Does an Aspirin a Day Keep the Doctor Away?

Aspirin is an old and venerable medication. The...

Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial

In a phase 2 study, kidney transplant recipients of low...

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