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Anti-TGF-{beta}1 Antibody Therapy in Patients with Diabetic Nephropathy

TGF-β has been implicated as a major pathogenic...

Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes

Tyrosine and serine/threonine signal-transduction...

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

The eukaryotic initiation factor 5A (eIF5A), which is...

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule

Kidneys contribute to glucose homeostasis by reabsorbing...

Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis

Kidney fibrosis initiates at certain focal sites in...

HDL Cholesterol Efflux Does Not Predict Cardiovascular Risk in Hemodialysis Patients

The cardioprotective effect of HDL is thought to be...

Hyperoxaluria Requires TNF Receptors to Initiate Crystal Adhesion and Kidney Stone Disease

Intrarenal crystals trigger inflammation and renal cell...

Progress in Understanding the Genetics of Calcium-Containing Nephrolithiasis

Renal stone disease is a frequent condition, causing a...

Moving Biomarkers toward Clinical Implementation in Kidney Transplantation

Long-term kidney transplant outcomes remain suboptimal,...

Bicarbonate Balance and Prescription in ESRD

The optimal approach to managing acid-base balance is...

Inflammation as a Therapeutic Target To Improve Vascular Function in Kidney Disease

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Should Transplant Referral Be a Clinical Performance Measure?

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HIV-1 Infection of Renal Cells in HIV-Associated Nephropathy

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Pericytes Preserve Capillary Integrity to Prevent Kidney Hypoxia

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Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone

Phosphate (Pi) homeostasis is regulated by renal,...

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