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Chronic Fluid Overload and Mortality in ESRD

Sustained fluid overload (FO) is considered a major...

(Pro)renin Receptor Is an Amplifier of Wnt/{beta}-Catenin Signaling in Kidney Injury and Fibrosis

The (pro)renin receptor (PRR) is a transmembrane protein...

Na+/HCO3- Cotransporter NBCn2 Mediates HCO3- Reclamation in the Apical Membrane of Renal Proximal Tubules

The kidney maintains systemic acid-base balance by...

Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures

In the live animal, tissue autofluorescence arises from...

Long-Term Endothelin-A Receptor Antagonism Provides Robust Renal Protection in Humanized Sickle Cell Disease Mice

Sickle cell disease (SCD)–associated nephropathy is a...

The MicroRNA-199a/214 Cluster Targets E-Cadherin and Claudin-2 and Promotes High Glucose-Induced Peritoneal Fibrosis

Serum response factor (SRF) was found to be involved in...

C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles

The kinin system is activated during vasculitis and may...

Erythropoietin Receptor-Mediated Molecular Crosstalk Promotes T Cell Immunoregulation and Transplant Survival

Although spontaneous kidney transplant acceptance/...

Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2

Hyperinsulinemic hypoglycemia (HI) and congenital...

Clinical and Genetic Spectrum of Bartter Syndrome Type 3

Bartter syndrome type 3 is a clinically heterogeneous...

Colon Cancer Screening among Patients Receiving Dialysis in the United States: Are We Choosing Wisely?

The American Society of Nephrology recommends against...

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Urine Ammonium and Preclinical Acidosis in CKD

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Turning the Tide: Improving Fluid Management in Dialysis through Technology

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Re-Examining Neutrophil Participation in GN

Significant advances in understanding the pathogenesis...

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