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Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation

In the kidney, formation of the functional filtration...

Mitogen-Activated Protein Kinase 14 Promotes AKI

An improved understanding of pathogenic pathways in AKI...

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

The eukaryotic initiation factor 5A (eIF5A), which is...

Inflammation as a Therapeutic Target To Improve Vascular Function in Kidney Disease

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Oxalobacter formigenes-Derived Bioactive Factors Stimulate Oxalate Transport by Intestinal Epithelial Cells

Hyperoxaluria is a major risk factor for kidney stones...

Vascular Function and Uric Acid-Lowering in Stage 3 CKD

Hyperuricemia may contribute to endothelial dysfunction...

Transmembrane TNF-{alpha} Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy

Studies have shown that podocytes and renal tubular...

A Randomized Trial to Reduce Disparities in Referral for Transplant Evaluation

Georgia has the lowest kidney transplant rates in the...

Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study

The rate of decline of renal function varies...

African Ancestry-Specific Alleles and Kidney Disease Risk in Hispanics/Latinos

African ancestry alleles may contribute to CKD among...

Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone

Phosphate (Pi) homeostasis is regulated by renal,...

Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection

CD73-derived adenosine plays an anti-inflammatory role...

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule

Kidneys contribute to glucose homeostasis by reabsorbing...

Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis

Kidney fibrosis initiates at certain focal sites in...

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

Genome-wide association studies have identified >50...

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