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Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation

In the kidney, formation of the functional filtration...

Transmembrane TNF-{alpha} Facilitates HIV-1 Infection of Podocytes Cultured from Children with HIV-Associated Nephropathy

Studies have shown that podocytes and renal tubular...

Proximal Tubule CD73 Is Critical in Renal Ischemia-Reperfusion Injury Protection

CD73-derived adenosine plays an anti-inflammatory role...

Acute Adaption to Oral or Intravenous Phosphate Requires Parathyroid Hormone

Phosphate (Pi) homeostasis is regulated by renal,...

African Ancestry-Specific Alleles and Kidney Disease Risk in Hispanics/Latinos

African ancestry alleles may contribute to CKD among...

Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study

The rate of decline of renal function varies...

A Randomized Trial to Reduce Disparities in Referral for Transplant Evaluation

Georgia has the lowest kidney transplant rates in the...

Vascular Function and Uric Acid-Lowering in Stage 3 CKD

Hyperuricemia may contribute to endothelial dysfunction...

Anti-TGF-{beta}1 Antibody Therapy in Patients with Diabetic Nephropathy

TGF-β has been implicated as a major pathogenic...

Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes

Tyrosine and serine/threonine signal-transduction...

Mitogen-Activated Protein Kinase 14 Promotes AKI

An improved understanding of pathogenic pathways in AKI...

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

The eukaryotic initiation factor 5A (eIF5A), which is...

HIV-1 Infection of Renal Cells in HIV-Associated Nephropathy

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Should Transplant Referral Be a Clinical Performance Measure?

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Inflammation as a Therapeutic Target To Improve Vascular Function in Kidney Disease

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