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CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis

The importance of the kidney distal convoluted tubule (...

Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation

Albuminuria is a key instigator of tubulointerstitial...

Indoxyl Sulfate Upregulates Liver P-Glycoprotein Expression and Activity through Aryl Hydrocarbon Receptor Signaling

In patients with CKD, not only renal but also, nonrenal...

Proteomic Profiling Reveals the Transglutaminase-2 Externalization Pathway in Kidneys after Unilateral Ureteric Obstruction

Increased export of transglutaminase-2 (TG2) by tubular...

ApoL1 Overexpression Drives Variant-Independent Cytotoxicity

Coding variants in the APOL1 gene are associated...

GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation

Collecting ducts make up the distal-most tubular...

Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury

The IL-33-type 2 innate lymphoid cell (ILC2) axis has an...

Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific {gamma}ENaC Knockout

The amiloride-sensitive epithelial sodium channel (ENaC...

Magnesium and Risk of Hip Fracture among Patients Undergoing Hemodialysis

Magnesium is an essential mineral for bone metabolism....

Causes of Death after a Hospitalization with AKI

Mortality after AKI is high, but the causes of death are...

Long-Term Clinical Outcomes after Early Initiation of RRT in Critically Ill Patients with AKI

Whether earlier initiation of RRT in critically ill...

Maternal and Fetal Outcomes of Pregnancies in Women with Atypical Hemolytic Uremic Syndrome

Atypical HUS (aHUS) is a disorder most commonly caused...

Fibrotic Venous Remodeling and Nonmaturation of Arteriovenous Fistulas

The frequency of primary failure in arteriovenous...

Control of Humoral Response in Renal Transplantation by Belatacept Depends on a Direct Effect on B Cells and Impaired T Follicular Helper-B Cell Crosstalk

Generation of de novo donor-specific antibodies...

Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans

Individuals with CKD are particularly predisposed to...

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