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Targeting mTOR Signaling Can Prevent the Progression of FSGS

Mammalian target of rapamycin (mTOR) signaling is...

A Novel Inhibitor of Homeodomain Interacting Protein Kinase 2 Mitigates Kidney Fibrosis through Inhibition of the TGF-{beta}1/Smad3 Pathway

Homeodomain interacting protein kinase 2 (HIPK2) is a...

Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury

Aminopeptidase A (APA) is expressed in glomerular...

Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells

Analysis of the immune system in the kidney relies...

Pals1 Haploinsufficiency Results in Proteinuria and Cyst Formation

The nephron is the basic physiologic subunit of the...

Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients

It is unclear whether warfarin is protective or harmful...

Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States

Increased urine albumin excretion is highly prevalent in...

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Fatal Dialysis Vascular Access Hemorrhage

Bleeding from dialysis vascular access (arteriovenous...

Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury

Sulfasalazine is an anti-inflammatory agent commonly...

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Combating chronic kidney disease with exercise

A research team is combating chronic kidney disease (CKD...

Intensive blood pressure lowering benefits patients with chronic kidney disease

In individuals with chronic kidney disease, targeting a...

Non-Dialysis CKD Patients With Anemia Have More CVD, Worse QoL

Anemic patients were 41% and 80% more likely to have...

Education Can Improve Phosphate Control

Patients receiving educational or behavioral...

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Is There a Role for Diaphoresis Therapy for Advanced Chronic Kidney Disease Patients?

Diaphoresis therapy to remove water and solutes for the...

Association of Hypertriglyceridemia With the Incidence and Progression of Chronic Kidney Disease and Modification of the Association by Daily Alcohol Consumption

The association of serum triglycerides (TGs) and alcohol...

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