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Chromatin Conformation Links Distal Target Genes to CKD Loci

Genome-wide association studies (GWASs) have identified...

Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus-Driven Hypertension in Diverse Diabetic Models

Progress in research and developing therapeutics to...

Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury

Diabetic nephropathy (DN) has become the single leading...

Reduced Expression of Glutathione S-Transferase {alpha}4 Promotes Vascular Neointimal Hyperplasia in CKD

Neointima formation is the leading cause of...

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis

microRNAs (miRNAs) are sequence-specific inhibitors of...

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

Intrinsic ureteropelvic junction obstruction is the most...

Overweight and Obesity Are Predictors of Progression in Early Autosomal Dominant Polycystic Kidney Disease

The association of overweight/obesity with disease...

Redirecting TGF-{beta} Signaling through the {beta}-Catenin/Foxo Complex Prevents Kidney Fibrosis

TGF-β is a key profibrotic factor, but targeting...

Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells

Acidosis is an important complication of AKI and CKD....

Artículos Científicos RSS ASN

Robotic Partial Nephrectomy Feasible for Larger Kidney Tumors

No greater risks for upstaging or positive surgical...

Bladder Cancer Risk Higher in Urinary Stone Formers

Patients with versus without a history of urinary...

Kidney Cancer Progression Linked to Preop Cardiovascular Biomarkers

Elevated serum levels of BNP and NT-proBNP prior to...

Diabetes in Pregnancy Raises Risk of Heart Disease

Women who have had gestational diabetes have an...

RCC Treatment Costs Could Negatively Affect Health

Access to treatment should be considered as important as...

Radical Nephrectomy Linked With Worse Kidney Function, Survival

Patients who underwent radical nephrectomy had 2-fold...

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