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Overcoming Barriers in Kidney Health--Forging a Platform for Innovation

Innovation in kidney diseases is not commensurate with...

The Histone Methyltransferase Enzyme Enhancer of Zeste Homolog 2 Protects against Podocyte Oxidative Stress and Renal Injury in Diabetes

Epigenetic regulation of oxidative stress is emerging as...

Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome

Monoclonal gammopathies are frequently complicated by...

Intracellular Phosphate Dynamics in Muscle Measured by Magnetic Resonance Spectroscopy during Hemodialysis

Of the 600–700 mg inorganic phosphate (Pi) removed...

Renal 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase Is an Important Determinant of AKI Severity after Ischemia-Reperfusion

A positional isomer of 3',5'-cAMP, 2',3'-cAMP, is...

Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus

To reduce lithium–induced nephrogenic diabetes insipidus...

Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression

Enhancer of zeste homolog 2 (EZH2) is a...

Urine Injury Biomarkers and Risk of Adverse Outcomes in Recipients of Prevalent Kidney Transplants: The Folic Acid for Vascular Outcome Reduction in Transplantation Trial

Recipients of kidney transplants (KTR) are at increased...

Racial and Ethnic Disparities in Use of and Outcomes with Home Dialysis in the United States

Home dialysis, which comprises peritoneal dialysis (PD)...

CKD Prevalence Varies across the European General Population

CKD prevalence estimation is central to CKD management...

Unlocking the Value of Variation in CKD Prevalence

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Role of Mitochondrial DNA in Septic AKI via Toll-Like Receptor 9

Toll-like receptor 9 (TLR9) contributes to the...

Megalin-Mediated Tubuloglomerular Alterations in High-Fat Diet-Induced Kidney Disease

Obesity, an important risk factor for metabolic syndrome...

Filgrastim-Induced Crescentic Transformation of Recurrent IgG2{lambda} GN

Proliferative GN with monoclonal IgG deposits is an...

Inhibitor of NF{kappa}B Kinase Subunit 2 Blockade Hinders the Initiation but Aggravates the Progression of Crescentic GN

The NFB transcription factor family facilitates...

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