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APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes

APOL1 harbors C–terminal sequence variants (G1...

APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death

People of African ancestry carrying certain APOL1 mutant...

Protein Kinase C{delta} Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity

Nephrotoxicity is a major adverse effect in cisplatin...

Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-{gamma}

Maladaptive repair after AKI may lead to progressive...

Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho

αKlotho (αKL) regulates mineral metabolism...

Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron

Tight control of extracellular and intracellular...

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Visceral Adipose Tissue and Leptin Hyperproduction Are Associated With Hypogonadism in Men With Chronic Kidney Disease

Hypogonadism is a common endocrine disorder in men with...

The Association Between the Metabolic Syndrome and Metabolic Syndrome Score and Urine Microalbumin/Urine Creatinine Ratio and Glomerular Filtration Rate in Korean Adults With Obesity

This study assessed the association between metabolic...

Tryptophan and Kynurenine Levels and Its Association With Sleep, Nonphysical Fatigue, and Depression in Chronic Hemodialysis Patients

Sleep and mood disorders are common in hemodialysis (HD...

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Risks of Adverse Events in Advanced CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study

People with advanced chronic kidney disease are at risk...

Kidney Injury and Repair Biomarkers in Marathon Runners

Investigation into strenuous activity and kidney...

Race, Serum Potassium, and Associations With ESRD and Mortality

Recent studies suggest that potassium levels may differ...

Unrecognized Fibrinogen A α-Chain Amyloidosis: Results From Targeted Genetic Testing

Fibrinogen A α-chain (AFib) amyloidosis results from...

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Scientists Discover New Class of Anti-Diabetes Compounds That Reduce Liver Glucose Production

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Diabetes drug could be the first to reverse the disease

Rising obesity is leading to a boom in type 2 diabetes....

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