Artículos Científicos en Ingles

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MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury

MicroRNAs have been implicated in ischemic AKI. However...

Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3

Muscle proteolysis in CKD is stimulated when the...

Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an {alpha}-Klotho-Deficient Model

Inorganic phosphate (Pi) has been implicated in the...

Re-Examining Risk of Repeated HLA Mismatch in Kidney Transplantation

Kidney retransplantation is a risk factor for decreased...

Race, APOL1 Risk, and eGFR Decline in the General Population

The APOL1 high-risk genotype, present in...

Candidate Surrogate End Points for ESRD after AKI

AKI, a frequently transient condition, is not accepted...

Predicted Mutation Strength of Nontruncating PKD1 Mutations Aids Genotype-Phenotype Correlations in Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD)...

IgA Structure Variations Associate with Immune Stimulations and IgA Mesangial Deposition

IgA1 mesangial deposition is the hallmark of IgA...

Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD

Kidney disease leads to clinically relevant disturbances...

Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy

Mitochondrial fission has been linked to the...

Distinct Requirements for Vacuolar Protein Sorting 34 Downstream Effector Phosphatidylinositol 3-Phosphate 5-Kinase in Podocytes Versus Proximal Tubular Cells

The mechanisms by which the glomerular filtration...

Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD

Studies have revealed many analogies between podocytes...

Renal Function Profile in White Kidney Donors: The First 4 Decades

Previous studies reported the risk of ESRD after kidney...

TRPC6 G757D Loss-of-Function Mutation Associates with FSGS

FSGS is a CKD with heavy proteinuria that eventually...

Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis

Inhibitors of EGF receptor (EGFR) have antifibrotic...

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