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Gene Editing: Powerful New Tools for Nephrology Research and Therapy

Biologic research is experiencing a transformation...

Pragmatic Clinical Trials in CKD: Opportunities and Challenges

Randomized controlled trials in CKD lag in number behind...

Pragmatic Trials in Maintenance Dialysis: Perspectives from the Kidney Health Initiative

Pragmatic clinical trials are conducted under the real-...

Developmental Origins for Kidney Disease Due to Shroom3 Deficiency

CKD is a significant health concern with an underlying...

Mesencephalic Astrocyte-Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress-Related Kidney Diseases

Endoplasmic reticulum (ER) stress and disrupted...

The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution

Common variants in the UMOD gene encoding...

Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition

The circadian clock controls a wide variety of metabolic...

MicroRNA-196a/b Mitigate Renal Fibrosis by Targeting TGF-{beta} Receptor 2

Organ-specific microRNAs have essential roles in...

Adjusting the 17{beta}-Estradiol-to-Androgen Ratio Ameliorates Diabetic Nephropathy

Diabetes is manifested predominantly in males in...

Sex Differences in Renal Proximal Tubular Cell Homeostasis

Studies in human patients and animals have revealed sex-...

Predicting Individual Renal Allograft Outcomes Using Risk Models with 1-Year Surveillance Biopsy and Alloantibody Data

The ability to predict outcomes for individual patients...

Artículos Científicos RSS ASN

Can Hypertension Raise Prostate Cancer Risk?

Data from 21 observational studies...

Leptin a Potential Target to Reduce CVD Risk in CKD-MBD

Parathyroidectomy may improve leptin...

High CRP Ups Kidney Failure Risk in Diabetic CKD Patients With Anemia

End-stage renal disease is 32% more...

Artículos Científicos RSS AJKD

Trends in Receipt of Intensive Procedures at the End of Life Among Patients Treated With Maintenance Dialysis

Many dialysis patients receive intensive procedures...

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