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The Loss of GSTM1 Associates with Kidney Failure and Heart Failure

Glutathione S-transferase mu 1 (GSTM1) encodes an...

Association between Endothelin-1 Levels and Kidney Disease among Blacks

Endothelin-1, a marker of endothelial dysfunction, is a...

Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism

Nephron progenitor cells (NPCs) show an age-dependent...

Lysophosphatidic Acid Receptor Antagonism Protects against Diabetic Nephropathy in a Type 2 Diabetic Model

Lysophosphatidic acid (LPA) functions through activation...

A Missense Mutation in the Extracellular Domain of {alpha}ENaC Causes Liddle Syndrome

Liddle syndrome is an autosomal dominant form of...

Yap/Taz Deletion in Gli+ Cell-Derived Myofibroblasts Attenuates Fibrosis

In damaged kidneys, increased extracellular matrix (ECM...

A Heterologous Model of Thrombospondin Type 1 Domain-Containing 7A-Associated Membranous Nephropathy

Thrombospondin type 1 domain-containing 7A (THSD7A) is a...

Compensatory Distal Reabsorption Drives Diuretic Resistance in Human Heart Failure

Understanding the tubular location of diuretic...

Extracellular Vesicles in Preeclampsia: Evolving Contributors to Proteinuria

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VTE Prophylaxis Inadequate for Acute Kidney Injury Patients

In a study, AKI sufferers had an increased rate of...

Stone Risk Greater In Wetter Climates

New study may redefine the "stone belt" in the United...

Intensive Blood Pressure Control May Not Benefit CKD Patients

Post hoc analysis of SPRINT finds no significant...

Skin may regulate blood pressure, study finds

The skin may respond to low-oxygen environments in a way...

KIDNEY TRANSPLANTATION MAY PROLONG THE SURVIVAL OF PATIENTS ON LONG-TERM DIALYSIS

• In a recent analysis of individuals on dialysis for at...

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Altered Serum n-6 Polyunsaturated Fatty Acid Profile and Risks of Mortality and Cardiovascular Events in a Cohort of Hemodialysis Patients

Alterations in the balance between serum n-3 and n-6...

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