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Acidosis and Deafness in Patients with Recessive Mutations in FOXI1

Maintenance of the composition of inner ear fluid and...

Control of Humoral Response in Renal Transplantation by Belatacept Depends on a Direct Effect on B Cells and Impaired T Follicular Helper-B Cell Crosstalk

Generation of de novo donor-specific antibodies...

Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans

Individuals with CKD are particularly predisposed to...

Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation

Albuminuria is a key instigator of tubulointerstitial...

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis

Human kidney function is underpinned by approximately 1,...

The UMOD Locus: Insights into the Pathogenesis and Prognosis of Kidney Disease

The identification of genetic factors associated with...

Targeting B Cells and Plasma Cells in Glomerular Diseases: Translational Perspectives

The unique contributions of memory B cells and plasma...

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney

Cellular interactions among nephron, interstitial, and...

Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion

The epithelial Wolffian duct (WD) inserts into the...

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning

The nephron is the functional unit of the kidney, but...

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney

Tamm–Horsfall protein (THP), also known as uromodulin,...

GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation

Collecting ducts make up the distal-most tubular...

ApoL1 Overexpression Drives Variant-Independent Cytotoxicity

Coding variants in the APOL1 gene are associated...

Salt-Losing Tubulopathies in Children: Whats New, Whats Controversial?

Renal tubulopathies provide insights into the inner...

Artículos Científicos RSS AJKD

Altered Prostaglandin Signaling as a Cause of Thiazide-Induced Hyponatremia

Thiazide diuretics are widely used in the management of...

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