US Organ Procurement Organization Donation Principles, Laws, and Practices

US organ procurement organizations (OPOs) are the world’s donation leaders,1,2 with 109 deceased donor transplantations per million population and a 38% increase in donations during the past 5 years (from 8,596 deceased donors in 2014 to 11,870 in 2019).3,4 This growth has helped decrease waiting lists by 10% during the past several years despite an increase in the prevalence of kidney failure.5 During the 2014 to 2019 period, donations have increased in 91% of the 58 OPOs (Table S1), with those achieving the greatest growth showing increases≥165% (Table 1).