Posttransplantation diabetes mellitus (PTDM) remains common after kidney transplantation, but controversy persists about its pathophysiologic mechanism.1,2 We previously found that insulin sensitivity at similar oral glucose tolerance test (OGTT)-derived 2-hour glucose concentrations ([Glc]2h) was higher in kidney transplant recipients (KTRs) than in non–transplant recipient general population controls, whereas insulin release was lower.3 Our earlier study lacked a transplant control group, and the KTR group comprised both tacrolimus- and cyclosporine-treated patients, although tacrolimus and cyclosporine portend meaningful differences in diabetes risk.