Mesoamerican nephropathy refers to a kidney disease that affects primarily male laborers (usually in the agricultural sector) without traditional risk factors such as diabetes and hypertension and has been mainly identified in regions of Central America.1 Similar kidney diseases have been reported in other regions of the world, such as India, Sri Lanka, and Egypt, as indicated by Ganguli.2 The term CKDu (chronic kidney disease of unknown etiology) is very broad and includes kidney disease due to diverse causes such as chronic glomerulonephritis, a kidney disease from a recognized condition that was not correctly diagnosed in the patient, and so on.