Several studies have established that if the effluent volume for continuous renal replacement therapy is greater than 20 to 25mL/kg/h, there is no difference in patient prognosis. The recent randomized controlled trial by Park et al1 showed no difference in mortality between the conventional (40mL/kg/h) and high-dose (80mL/kg/h) groups. A number of prior studies addressed the same set of issues related to dialysis dose in continuous dialysis therapy. Ronco et al2 reported in 2000 that the dose should reach 35mL/kg/h.