Kidney disease is a common manifestation in HIV-infected patients, with albuminuria reported in 10%-15%. The vast majority, around 90%, of HIVAN patients are of African descent. Patients may present at any age. The spectrum of disease in HIV-infected patients varies, from HIVAN, which is manifest by collapsing glomerulopathy, to other forms of FSGS, minimal change disease, thrombotic microangiopathy, and lupus-like HIV-immune complex kidney disease (HIVICK). Kidneys are often enlarged in HIVAN patients.