Functional, histological and biochemical consequences of renal lymph disorder in mononephrectomized rats.

Conclusions: Disturbance of renal lymph circulation induces severe chronic renal lesions, chronic renal failure and enhanced renal cell apoptosis. The Bax/Bcl-2 pathway mediates apoptosis in this disease.
PMID: 19229825 [PubMed - in process] (Source: Journal of Nephrology)