Therapeutic tools for dyslipidemia in peritoneal dialysis patients.
Authors: Scarpioni R
Patients on peritoneal dialysis (PD) are at high cardiovascular (C-V) risk, and dyslipidemia, one of the major traditional C-V risk factors, is a common complication in chronic kidney disease. PD treatment may worsen lipid profile, because it confers a more atherogenic state than hemodialysis. There is evidence that in the general population, lipid-lowering therapy reduces C-V mortality, both in terms of primary and secondary prevention. The association between dyslipidemia and C-V mortality in dialysis patients is not well defined, and hypocholesterolemia, related to malnutrition/inflammation, is a confounding factor. However, despite the unfavorable lipid profile in PD patients and their high C-V mortality rate, until now we have had no conclusive data that the t...