Conclusions: We conclude that measurement of albuminuria by HPLC in long-term -80°C stored urine gives unreliable results. Decrease of HPLC-detected albuminuria is pH-dependent and may be due to the reducing capacity of urine. Prospective studies need to decide whether the predictive properties of HPLC-detected albuminuria decrease during longterm storage.
PMID: 19557717 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)