Asymmetric dimethylarginine, vascular calcifications and parathyroid hormone serum levels in hemodialysis patients.

Conclusions: Despite the results of bivariate analysis showing a linkage between ADMA and cardiac and coronary calcifications, regression analysis showed only a spurious association. The strong positive correlation between ADMA and LnPTH, validated by the regression analysis, may suggesta link between ADMA and PTH-derived vascular damage. ADMA levels could be influenced by the severity of hyperparathyroidism and contribute to cardiovascular death linked to PTH of hemodialysis patients.
PMID: 19809994 [PubMed - in process] (Source: Journal of Nephrology)