Renal ss2-adrenoceptor blockade worsens the outcome of an induced Escherichia coli renal infection.
Conclusions: The blockade of a renal beta2-AR signaling cascade aggravates inflammatory responses in the infected kidney, changes serum levels of cytokines, NO, and noradrenaline, and leads to renal dysfunction and a higher rate of mortality.
PMID: 20349426 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)