Warfarin: to use or not to use in chronic kidney disease patients?

Authors: Cozzolino M, Brandenburg V
Is the risk of major bleeding the only reason to be concerned about oral anticoagulant therapy in chronic kidney disease patients? We consider another potential adverse effect of long-term Coumadin use in chronic kidney disease patients as comparably devastating: the threat of inducing creeping vascular calcification.
PMID: 20349408 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)