Discussion: Impaired glucose tolerance complicated with hypertension leads to tubulointerstitial fibrosis in rat kidney. Imidazolone deposition and renin production in peritubular capillary endothelial cells may play a role in the development of tubulointerstitial fibrosis.
PMID: 21484732 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)