Incident isolated 1,25(OH)2D3 deficiency is more common than 25(OH)D deficiency in CKD.

Conclusions: The high incidence of new isolated 1,25(OH)2D deficiency as compared with new 25(OH)D deficiency, in the presence of 25(OH)D sufficiency, brings into question the value of measuring 25(OH)D levels in CKD. The significance of these findings and implications for replacement strategies require further study.
PMID: 21688248 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)