Nrf2 and Sp family synergistically enhance the expression of ion transporters in potassium-depleted conditions.
Conclusion: These results suggest that Nrf2 mediates transcriptional activation of colonic H/K-ATPase and kNBC1 in response to K-depleted stress and augments Sp family-mediated expression of these ion transporters.
PMID: 21725920 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)