Authors: Minetti EE
After 50 years, the incidence of lymphocele and lymphorrhea associated with renal transplantation remains substantially high in spite of more accurate surgical technique, reduction of other complications and improvement of general outcomes. The data from the literature point to the allograft as the source of increased lymph production, which in spite of an accurate hilar lymphatics ligature, can find a transcapsular outlet. Subclinical and clinical graft rejection and inflammation greatly enhance lymph production and leakage. This mechanism may partially mediate the effects of some immunosuppressive drugs on the incidence of lymphocele.
PMID: 21748721 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)