Conclusions: Our data suggest that FSGS patients excreting large amounts of PDX-positive cells in their urine have a better outcome regarding kidney function and proteinuria compared with patients without excretion of PDX-positive cells. These data imply that PDX-positive cells have a positive effect on podocyte regeneration in FSGS patients.
PMID: 22241637 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)