Conclusion: The results suggest that the CTLA4 gene +49A/G polymorphism may be a possible genetic susceptibility locus for acute rejection. The results of the present meta-analysis may be limited by a number of factors including inadequate total sample size and poor statistics, and should be interpreted with caution. Further confirmation in large and well-designed studies are needed.
PMID: 22307437 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)