Authors: Onder G, Corsonello A, Vetrano DL
Abstract
The aging process is characterized by a high level of complexity, which makes the care of older adults particularly challenging. This complexity results from the presence of an array of concomitant clinical conditions, whose integration and cumulative effect result in different degrees of functional deficits, cognitive deterioration, nutritional problems, geriatric syndromes in addition to lack of social support and financial resources. The presence of these factors may reduce the efficacy of prescribed drugs and increase the risk of iatrogenic illness making the pharmacologic treatment of this complex patient a difficult task for the prescribing physician. The presence of renal disease further contributes to increasing this compl...