Losartan preserves glomerular basement membrane anionic charge sites in a rat model of nephropathy.

Conclusions: A rat model of nephropathy indicates that losartan reduces urinary protein and preserves the number of anionic sites on the GBM, but has no apparent effect on hemodynamics.
PMID: 23065922 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)