Cardiovascular disease (CVD) is the leading cause of death worldwide, with patients with advanced chronic kidney disease (CKD) being at a particularly high risk.1,2 A key player in CVD is low-density lipoprotein (LDL) cholesterol, an atherogenic lipoprotein that delivers cholesterol to artery walls and is strongly associated with atherosclerotic cardiovascular disease (ASCVD).3 Another significant, though often underappreciated, factor contributing to ASCVD is aldosterone.4