Proteinuria and VEGF-targeted therapies: 
an underestimated toxicity?

This report is based on our personal experience with 78 patients developing renal problems with anti-VEGF therapy. We found that proteinuria induced by anti-VEGF therapy, even if weak and without associated renal insufficiency, may reflect a serious histological renal disease.
PMID: 24052461 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)