We read with interest the recent Journal of Renal Nutrition article examining whether biomarker-assessed endogenous acid loads and phosphate excretion during growth are prospectively associated with adult circulating uromodulin in participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed cohort (n = 358).1 The authors report an inverse association between higher long-term net acid excretion (NAE) during childhood/adolescence and lower adult circulating uromodulin, alongside a positive association with higher urinary pH, whereas urinary phosphate excretion and urinary potential renal acid load (uPRAL) showed no significant relationships.