HBx inhibits proliferation and induces apoptosis via Fas/FasL upregulation in rat renal tubular epithelial cells.
Conclusions: Our results suggest that HBx induces apoptosis in NRK-52E cells, at least in part through activation of the Fas/FasL pathway. The activation of caspase-8 appears to mediate the induction of apoptosis.
PMID: 24249212 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)
