Remote ischemic preconditioning (RIPC) was first described by Przyklenk et al1 in 1993, when dogs exposed to occlusion of the right circumflex artery experienced protection of the myocardium supplied by the left anterior descending artery. RIPC is achieved by producing a brief ischemic insult to one area of the body to induce protection to a remote site. Clinical studies have usually induced RIPC with a blood pressure cuff on the arm or leg to produce transient ischemia. Generally, the cuff is inflated to 200 mm Hg or 50 mm Hg above the systolic atrial pressure for 5-10 minutes, typically under anesthesia.