CONCLUSION: This study suggests that AVF failure is associated with an increased adventitial fibrosis, myofibroblast activation and capillary rarefaction, potentially linked with endothelial-to-mesenchymal transition. In this scenario, our data suggest that PDGF may play a pathogenic role.
PMID: 24574138 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)