Administration of IL-1ra improves adiponectin levels in chronic hemodialysis patients.

CONCLUSIONS: Short-term administration of IL-1ra significantly increased adiponectin levels among prevalent MHD patients. The intervention did not impact insulin sensitivity parameters. Studies of longer duration and larger sample size are needed to further evaluate the potential effect of anti-inflammatory interventions on metabolic markers and insulin sensitivity in MHD patients.
PMID: 24609887 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)