Current dietary guidelines for management of chronic kidney disease (CKD) focus on plant-based protein consumption without enough attention given to consumption of mushrooms. This is a missed opportunity since these members of the Fungi kingdom provide high amounts of rare distinctive nutrients and bioactives. We have perused most of the data on nutritional aspects of mushrooms published over the past decade with the goal to introduce nephrology health care professionals to the broad scope of health benefits that increased mushroom consumption might offer in the dietary management of CKD patients.