We read with interest the study by Teitelbaum et al. published in AJKD “Associations Between Serum Sodium, Peritoneal Dialysis–Associated Peritonitis, and Mortality in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS)[1].” This analysis of 23,707 peritoneal dialysis (PD) patients across 8 countries revealed a significant association between serum sodium levels and all-cause mortality (reverse J-shaped relationship), while no clear link with peritonitis risk was found. These findings provide crucial clinical evidence for electrolyte management in PD patients.