Cumulative iron dose and resistance to erythropoietin.

DISCUSSION: In ESA-treated patients cumulative Fe dose could be a useful tool to monitor the appropriateness of Fe therapy and to prevent iron overload. To establish whether the associations between cumulative iron dose, ERI and hospitalization risk are causal or attributable to selection bias by indication, clinical trials are necessary.
PMID: 25091785 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)