Chronic kidney disease progression is mainly associated with non-recovery of acute kidney injury.

CONCLUSIONS: Incomplete recovery of AKI was related with accelerated CKD-progression. Episodes of AKI were not associated with an accelerated decline of kidney function once the AKI episode had resolved. In the group without AKI episode, the progression was similar to that of the general population without CKD.
PMID: 25700932 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)