Machine Perfusion in Deceased Donor Kidney Transplantation: Promises of Improved Outcomes but Gaps in Implementation

Kidney transplantation is the preferred treatment for most patients with end-stage renal disease, as it prolongs survival and improves quality of life when compared to dialysis.1,2 Inherent in the act of transplantation, the donor organ experiences a period of ischemia as it travels from the donor to reperfusion in the recipient. A ripe field of research is understanding and manipulating this ischemic period to minimize reperfusion injury, enhance organ quality assessment, and potentially modify outcomes and/or increase organ utilization.