The Impact of Kidney Transplantation on a Breadth of Cognitive Measures

Cognitive impairment is pervasive among kidney failure patients, reducing the chance of listing for kidney transplant (KT)1,2 and increasing time until KT for those who are listed.2 Yet, KT is the preferred form of kidney replacement therapy3 and has been shown to improve cognition.2,4,5 Cognitive impairment also has major implications on patients post-KT, impacting their health, graft survival, quality of life, and risk of mortality.2,5,6 While transplant institutes consider cognition when determining transplant eligibility, both patients and clinical experts argue that cognitive impairment alone should not be a contraindication for KT,7,8 particularly if certain cognitive domains can recover post-KT.