Immunoglobulin A (IgA)-dominant infection-related glomerulonephritis is a morphologic variant of acute infection-related glomerulonephritis that typically occurs in association with staphylococcal infection. It is most common in older patients and those with diabetes, and rare in children. Patients typically present with acute kidney injury, proteinuria, and hematuria. Hypocomplementemia is present in the vast majority of the patients. The prognosis is poor, with less than 20% of patients fully recovering kidney function, most likely owing to age-related underlying kidney changes and comorbidities, including diabetic kidney disease.