The kidneys are the most important regulators of potassium homeostasis and kidney disease is the principal determinant of dyskalemias, especially hyperkalemia.1 Both hypokalemia and hyperkalemia are clinically relevant abnormalities, mainly owing to their known propensity to induce cardiac arrhythmias.2 Several studies have examined the association of plasma potassium concentration and various clinical outcomes. These have included individuals with normal kidney function and those with chronic kidney disease (CKD) not requiring kidney replacement therapy (KRT), as well as patients with kidney failure on dialysis, and examined both short-term and long-term associations with outcomes including all-cause mortality, cardiovascular mortality, and end-stage kidney failure.