Association of circulating Trimethylamine-N oxide with malnutrition and the risk of coronary artery disease in patients with maintenance hemodialysis

Malnutrition is a serious complication frequently observed in dialysis patients. Therefore, nutrition status evaluation and the early identification of malnutrition is clinicallyimportant. Trimethylamine N-oxide (TMAO) is reportedly associated with deteriorating metabolic profiles and cardiovascular diseases. The aim of our study was to investigate correlationsbetween circulating TMAO levels and malnutrition and the risk of Major Adverse Cardiovascular Events (MACEs) in patients on maintenance hemodialysis (MHD).